sequence_analysis

Integrating Protein Structural Dynamics and Evolutionary Analysis

The Grant lab are lead developers of Bio3D, an open source R package for the exploratory analysis of protein sequence, structure and dynamic trajectory data.



Features of the package include extensive graphical and statistical capabilities, atom selection, rigid core superposition, clustering, distance matrix analysis, structure and sequence conservation analysis and principal component analysis.
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Target Selection in Structural Genomics

We collaborate in the development of sgTarget, an informatics resource capable of performing target selection for structural genomics projects through the implementation of a number of sequence analysis protocols.

The system enables structural biologists to select targets from their genomic sequences of interest, according to their research needs.

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